Diagnosis

The   diagnosis   is   made   clinically.   Histological   assessment may reveal marked hyperkeratosis, confluent parakeratosis, follicular plugging, acanthosis, spongiosis with lymphocyte, and neutrophil exocytosis with keratinocyte necrosis and dyskeratosis.[129]  It has been proposed that histopathologic features and tissue molecular profile of HIV-associated seborrhoeic dermatitis are different from those found in immunocompetent patients, but they are not still considered pathognomonic.[130], [131]